Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282738 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL13255969 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL12962952 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL29363675 | 0.80 | TRPM4 (0.57) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL28653 | 0.80 | TRPM4 (0.57) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL29518518 | 0.80 | CYP2A6 (0.55) | ALDH1A1CYP1A2ALOX12TDP1CYP2A6 | |
| SCHEMBL234439 | 0.80 | CYP2A6 (0.55) | ALDH1A1CYP1A2ALOX12TDP1CYP2A6 | |
| SCHEMBL29750056 | 0.80 | TRPM4 (0.57) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL15093210 | 0.80 | LMNA (0.46) | KDM4EALDH1A1HPGDCYP1A2MAPT | |
| SCHEMBL11753298 | 0.78 | CYP1A2 (0.59) | KDM4EALDH1A1HPGDCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173892-B2 | Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same | UNIVERSITE NICE SOPHIA ANTIPOLIS (FR) | 2015-11-03 | — | — | US | claimed |
| EP-2699240-B1 | ACADESINE DERIVATIVES, PRODUCTS AND COMPOSITIONS INCLUDING SAME, THERAPEUTIC USES THEREOF, AND METHODS FOR SYNTHESIZING SAME | UNIVERSITÉ NICE SOPHIA ANTIPOLIS (FR) | 2015-05-27 | — | — | EP | claimed |
| US-20140312270-A1 | Use of Carbonium Ion Scavengers in the Treatment of Lignocellulosic Biomass | ETH ZURICH (CH) | 2014-10-23 | — | — | US | claimed |
| EP-2776620-A1 | USE OF CARBONIUM ION SCAVENGERS IN THE TREATMENT OF LIGNOCELLULOSIC BIOMASS | ETH Zürich (CH) | 2014-09-17 | — | — | EP | claimed |
| US-20140179626-A1 | ACADESINE DERIVATIVES, PRODUCTS AND COMPOSITIONS INCLUDING SAME, THERAPUETIC USES THEREOF, AND METHODS FOR SYNTHESIZING SAME | INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE (FR) | 2014-06-26 | — | — | US | claimed |
| CN-103619332-A | Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same | UNIV NICE SOPHIA ANTIPOLIS | 2014-03-05 | — | — | CN | claimed |
| WO-2013068092-A1 | USE OF CARBONIUM ION SCAVENGERS IN THE TREATMENT OF LIGNOCELLULOSIC BIOMASS | ETH ZURICH (CH) | 2013-05-16 | — | — | WO | claimed |
| EP-1404763-B8 | METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS | CIBA SC HOLDING AG (CH) | 2007-10-10 | — | — | EP | claimed |
| EP-1404763-A1 | METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS | Ciba Specialty Chemicals Holding Inc. (CH) | 2004-04-07 | — | — | EP | claimed |
| WO-2002094945-A1 | METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-11-28 | — | — | WO | claimed |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | SHANGHAI EAST HOSPITAL (CN) | 2025-01-07 | — | — | US | disclosed |
| WO-2024147153-A1 | PEPTIDE-HISTIDINAL CONJUGATES AS AN ANTI-MALARIAL AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024145053-A1 | TYRAMIDE AND TYRAMIDE ANALOG CONJUGATES AND USES THEREOF FOR BIOLOGICAL TARGET STAINING PROCEDURES | Life Technologies Corporation (US) | 2024-07-04 | — | — | WO | disclosed |
| CN-114401935-B | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2024-04-05 | — | — | CN | disclosed |
| CN-117486682-A | Preparation method of functionalized beta-naphthalenyl ether compound | 中国海洋石油集团有限公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-1186962-A2 | Toner | CANON KABUSHIKI KAISHA (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-4560810-A | CHROMIUM OXIDE CATALYST CONTAINING AN OXIDE OF ZINC,IRON, MAGNESIUM, OR MANGANESE | GENERAL ELECTRIC COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | CACNA1F, CACNA1S, CACNA1D | KDM4E 3795/4885ALDH1A1 1001/4885HPGD 633/4885 |
| US-20140179626-A1 | ACADESINE DERIVATIVES, PRODUCTS AND COMPOSITIONS INCLUDING SAME, THERAPUETIC USES THEREOF, AND METHODS FOR SYNTHESIZING SAME | MCL1, ALOX15, ALOX12 | KDM4E 2715/4885ALDH1A1 1038/4885HPGD 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.