SCHEMBL6282738

SCHEMBL6282738

Cc1cc2cc(C)c(O)cc2cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
MAPT P10636 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
G6PD P11413 1/20 0.55
CYP2C9 P11712 1/20 0.55
PKM P14618 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 1/20 0.55
CCR6 P51684 1/20 0.55
HIF1A Q16665 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13255969 1.00 KDM4E (0.55) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL12962952 0.97 KDM4E (0.52) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL15581098 0.94 KDM4E (0.50) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL6346339 0.87 KDM4E (0.48) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL171209 0.83 KDM4E (0.52) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL8340170 0.83 CYP1A2 (0.59) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL297445 0.83 ESR2 (0.52) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL11753298 0.83 CYP1A2 (0.59) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL29771833 0.83 ESR2 (0.52) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL15920615 0.83 ESR2 (0.52) KDM4EMAPTALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2345682-B1 POLYMER ELECTROLYTE MEMBRANE LG CHEMICAL LTD (KR) 2017-08-23 EP disclosed
EP-1828278-B1 BRANCHED AND SULPHONATED MULTI BLOCK COPOLYMER AND ELECTROLYTE MEMBRANE USING THE SAME LG CHEMICAL LTD (KR) 2011-01-26 EP disclosed
US-20100167165-A1 COPOLYMER, POLYMER ELECTROLYTE, AND USE THEREOF SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-01 US disclosed
WO-2010055291-A1 NOVEL POLYMERIC MATERIALS SMITH & NEPHEW PLC (GB) 2010-05-20 WO disclosed
US-20100104985-A1 COMPOUND FOR PHOTORESIST, PHOTORESIST LIQUID, AND ETCHING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-6906046-B2 Pharmaceutical uses and synthesis of benzobicyclooctanes CELLTECH R & D INC. (US) 2005-06-14 US disclosed
US-20030069305-A1 Pharmaceutical uses and synthesis of benzobicyclooctanes CELLTECH R & D, INC. 2003-04-10 US disclosed
WO-2002051851-A2 PHARMACEUTICAL USES AND SYNTHESIS OF BENZOBICYCLOOCTANES CELLTECH R & D, INC. (US) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104985-A1 COMPOUND FOR PHOTORESIST, PHOTORESIST LIQUID, AND ETCHING METHOD USING THE SAME PYCR1, STK10, STK4 KDM4E 616/4885MAPT 264/4885ALDH1A1 3885/4885
US-20030069305-A1 Pharmaceutical uses and synthesis of benzobicyclooctanes CXCL8, CASP8, IL18 KDM4E 4510/4885MAPT 2701/4885ALDH1A1 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.