SCHEMBL1712271

SCHEMBL1712271

Fc1ccc(Oc2cc[c]cn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HSPB1 P04792 2/20 0.44
HTT P42858 1/20 0.44
GAA P10253 1/20 0.36
MMP13 P45452 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
SOS1 Q07889 1/20 0.34
TRPA1 O75762 2/20 0.34
SCN4A P35499 2/20 0.34
HRH3 Q9Y5N1 4/20 0.34
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2753392 0.84 KDM4E (0.34) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL2894972 0.81 MEN1 (0.52) MEN1KMT2AKDM4EALDH1A1HTT
SCHEMBL2901814 0.81 L3MBTL1 (0.44) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL2899323 0.81 MAPT (0.39) MEN1KMT2AKDM4EALDH1A1HTT
SCHEMBL2903058 0.81 MEN1 (0.44) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL315475 0.81 ALDH1A1 (0.43) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL2894791 0.81 MAPT (0.43) KDM4E
SCHEMBL2750901 0.81 MAP4K4 (0.43) MEN1KMT2AKDM4EALDH1A1L3MBTL1
SCHEMBL2903371 0.81 SCN5A (0.37) L3MBTL1
SCHEMBL19211767 0.81 MEN1 (0.36) MEN1KMT2AKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146518-A A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof 苏州爱玛特生物科技有限公司 2016-11-23 CN disclosed
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-4954497-A AGRICULTURE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0330939-A2 Acrylic acid morpholides, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MEN1 1798/4885KMT2A 1924/4885KDM4E 3733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.