Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 10/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903224 | 0.98 | MAPT (0.43) | MAPTNPSR1LMNALIPETHRB | |
| SCHEMBL2894167 | 0.85 | L3MBTL1 (0.39) | MAPTNPSR1LMNALIPETHRB | |
| SCHEMBL2903371 | 0.83 | SCN5A (0.37) | MAPTLMNALIPERAB9AKCNH2 | |
| SCHEMBL2901946 | 0.83 | RAB9A (0.54) | MAPTNPSR1LMNARAB9AKDM4E | |
| SCHEMBL693766 | 0.81 | L3MBTL1 (0.54) | MAPTNPSR1RAB9AKDM4EMAPK1 | |
| SCHEMBL1712271 | 0.81 | MEN1 (0.50) | KDM4E | |
| SCHEMBL2901251 | 0.80 | PTPRZ1 (0.44) | MAPTNPSR1LMNARAB9AKDM4E | |
| SCHEMBL2902798 | 0.79 | THRB (0.35) | MAPTNPSR1LMNALIPETHRB | |
| SCHEMBL2894972 | 0.77 | MEN1 (0.52) | MAPTNPSR1LMNALIPERAB9A | |
| SCHEMBL2899323 | 0.77 | MAPT (0.39) | MAPTTHRBKDM4EMAPK1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-4954497-A | AGRICULTURE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0330939-A2 | Acrylic acid morpholides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | MAPT 3480/4885NPSR1 1841/4885LMNA 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.