Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752900 | 0.87 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL2894972 | 0.85 | MEN1 (0.52) | MEN1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL7953772 | 0.83 | ALDH1A1 (0.55) | MEN1ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2752841 | 0.82 | CA2 (0.47) | MEN1ALDH1A1KMT2AHTTL3MBTL1 | |
| SCHEMBL2899323 | 0.81 | MAPT (0.39) | MEN1ALDH1A1KMT2AHTTLTA4H | |
| SCHEMBL1712271 | 0.81 | MEN1 (0.50) | MEN1ALDH1A1KMT2AHTTL3MBTL1 | |
| SCHEMBL2901814 | 0.81 | L3MBTL1 (0.44) | MEN1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL315475 | 0.81 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL2901946 | 0.81 | RAB9A (0.54) | MEN1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL2894886 | 0.81 | HRH3 (0.38) | MEN1ALDH1A1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146518-A | A kind of bruton's tyrosine kinase inhibitor intermediate and preparation method thereof | 苏州爱玛特生物科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-4954497-A | AGRICULTURE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0330939-A2 | Acrylic acid morpholides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | MEN1 2671/4885ALDH1A1 551/4885KMT2A 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.