SCHEMBL17127355

SCHEMBL17127355

COc1ccc(Oc2ccc(C(=O)C(SCC(C)OC(C)C)C(C)(C)C)cc2)c(OC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.39
▸ HTT P42858 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPT P10636 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ NPC1 O15118 3/20 0.35
▸ TP53 P04637 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ LMNA P02545 2/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ CA12 O43570 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ CA7 P43166 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ CA14 Q9ULX7 1/20 0.34
▸ SLC2A1 P11166 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127357 0.88 SLC2A1 (0.41) HTTALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL17127329 0.82 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2
SCHEMBL17126975 0.80 TTR (0.39) TTRHTTALDH1A1MAPTNPSR1
SCHEMBL17127363 0.71 PARP10 (0.46) HTTALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL17126983 0.69 SMN1; SMN2 (0.36) HTTALDH1A1MAPTNPC1SMN1; SMN2
SCHEMBL17126974 0.68 PARP10 (0.46) HTTALDH1A1SMN1; SMN2LMNACA1
SCHEMBL17126857 0.67 APP (0.36) HTTMAPTNPSR1GAANPC1
SCHEMBL17127023 0.67 KDM4E (0.37) HTTALDH1A1MAPTNPSR1NPC1
SCHEMBL17127027 0.67 PARP10 (0.44) HTTALDH1A1SMN1; SMN2LMNACA1
SCHEMBL17126862 0.67 AKR1C3 (0.39) HTTALDH1A1SMN1; SMN2LMNASLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS TTR 2210/4885HTT 1863/4885ALDH1A1 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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