SCHEMBL17127357

SCHEMBL17127357

COc1ccc(Oc2ccc(C(=O)C(SCC(C)OC(C)C)C(C)(C)C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 1/20 0.41
▸ PARP10 Q53GL7 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.40
▸ LMNA P02545 3/20 0.40
▸ HTT P42858 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ MEN1 O00255 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ TDP1 Q9NUW8 3/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ CES2 O00748 1/20 0.36
▸ CES1 P23141 1/20 0.36
▸ MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127329 0.91 ALDH1A1 (0.39) PARP10ALDH1A1SMN1; SMN2
SCHEMBL17127355 0.88 TTR (0.39) SLC2A1ALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL17127356 0.85 MEN1 (0.38) ALDH1A1LMNAHTTSMN1; SMN2MEN1
SCHEMBL17127363 0.82 PARP10 (0.46) SLC2A1PARP10ALDH1A1LMNAHTT
SCHEMBL17126974 0.78 PARP10 (0.46) SLC2A1PARP10ALDH1A1LMNAHTT
SCHEMBL17127027 0.77 PARP10 (0.44) SLC2A1PARP10ALDH1A1LMNAHTT
SCHEMBL17126973 0.76 SMN1; SMN2 (0.43) SLC2A1PARP10ALDH1A1LMNAHTT
SCHEMBL17126981 0.72 PARP10 (0.44) PARP10ALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL15935680 0.72 SMN1; SMN2 (0.46) SLC2A1ALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL17127365 0.71 PARP10 (0.45) PARP10ALDH1A1LMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS SLC2A1 4878/4885PARP10 611/4885ALDH1A1 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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