SCHEMBL17127356

SCHEMBL17127356

CC(C)OC(C)CSC(C(=O)c1ccc(Oc2ccc3ccccc3c2)cc1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ GABBR2 O75899 1/20 0.36
▸ GABBR1 Q9UBS5 1/20 0.36
▸ DGAT1 O75907 1/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ BRAF P15056 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC7 Q8WUI4 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ HDAC10 Q969S8 1/20 0.35
▸ HDAC11 Q96DB2 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ HDAC9 Q9UKV0 1/20 0.35
▸ HDAC5 Q9UQL6 1/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ NPC1 O15118 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17127329 0.90 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1PPARABCL2MCL1
SCHEMBL17127357 0.85 SLC2A1 (0.41) MEN1KMT2AL3MBTL1HDAC3HDAC4
SCHEMBL17127364 0.84 PPARG (0.40) MEN1KMT2AL3MBTL1GABBR2GABBR1
SCHEMBL17126978 0.81 CETP (0.40) MEN1KMT2AGABBR2GABBR1HDAC3
SCHEMBL17127028 0.80 CETP (0.42) HDAC3HDAC1HDAC2SMN1; SMN2NPC1
SCHEMBL17127355 0.79 TTR (0.39) SMN1; SMN2NPC1RAB9AALDH1A1LMNA
SCHEMBL17127022 0.79 PTGS2 (0.38) MEN1KMT2AL3MBTL1GABBR2GABBR1
SCHEMBL17126981 0.73 PARP10 (0.44) MEN1KMT2AL3MBTL1HDAC3SMN1; SMN2
SCHEMBL17126862 0.70 AKR1C3 (0.39) GABBR2GABBR1SMN1; SMN2ALDH1A1LMNA
SCHEMBL17127026 0.69 HDAC3 (0.47) HDAC3NPC1RAB9AALDH1A1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS MEN1 3840/4885KMT2A 1775/4885L3MBTL1 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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