Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475048 | 0.86 | ALDH1A1 (0.60) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL17273804 | 0.86 | ALDH1A1 (0.60) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL26194682 | 0.85 | ADORA2A (0.50) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL24303191 | 0.82 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL24303403 | 0.80 | ADORA2A (0.50) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL29564016 | 0.79 | ALDH1A1 (0.68) | ADORA2AADORA3ALOX15ALDH1A1HSD17B10 | |
| SCHEMBL169282 | 0.79 | ALDH1A1 (0.68) | ADORA2AADORA3ALOX15ALDH1A1HSD17B10 | |
| SCHEMBL16246145 | 0.79 | L3MBTL1 (0.61) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| SCHEMBL18347063 | 0.78 | ADORA2A (0.51) | ADORA2AADORA1ADORA3ADORA2BALOX15 | |
| Aniline SCHEMBL28441285 | 0.78 | ALDH1A1 (0.60) | ADORA3ALOX15TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344607-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2011-07-20 | — | — | EP | disclosed |