SCHEMBL16246145

SCHEMBL16246145

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.61
ADORA2A P29274 3/20 0.59
ADORA1 P30542 3/20 0.59
ADORA3 P0DMS8 2/20 0.59
ADORA2B P29275 2/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
POLB P06746 2/20 0.54
RAB9A P51151 4/20 0.52
NPC1 O15118 3/20 0.52
MAPK1 P28482 3/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
GPR55 Q9Y2T6 1/20 0.48
HTT P42858 1/20 0.48
NTSR1 P30989 1/20 0.45
NR1H4 Q96RI1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19497485 0.97 L3MBTL1 (0.58) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL12853994 0.97 L3MBTL1 (0.58) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL19497486 0.97 L3MBTL1 (0.58) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL21922946 0.95 L3MBTL1 (0.56) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL24312407 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL17720964 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL12854006 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL19762187 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL19762124 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL19497490 0.93 L3MBTL1 (0.54) L3MBTL1ADORA2AADORA1ADORA3ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293405-A1 Compositions Comprising UV-Filters and One or More (Bio)-Alkanediols SYMRISE AG (DE) 2023-09-21 US claimed
EP-4103144-A1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2022-12-21 EP claimed
WO-2022122894-A1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO claimed
US-20230293405-A1 Compositions Comprising UV-Filters and One or More (Bio)-Alkanediols SYMRISE AG (DE) 2023-09-21 US disclosed
CN-116528824-A Composition comprising an ultraviolet filter and one or more (bio) -alkanediols 西姆莱斯股份公司 2023-08-01 CN disclosed
WO-2023139037-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
WO-2023139038-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
EP-4103144-A1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2022-12-21 EP disclosed
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-06-16 US disclosed
WO-2022122894-A1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO disclosed
EP-3937883-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-01-19 EP disclosed
WO-2020182936-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2020-09-17 WO disclosed
EP-3227016-B1 MICROCAPSULES BASF SE (DE) 2020-08-26 EP disclosed
US-10709645-B2 Microcapsules BASF SE (DE) 2020-07-14 US disclosed
US-20170360660-A1 MICROCAPSULES BASF GRENZACH GMBH (DE) 2017-12-21 US disclosed
EP-2994201-B1 COMPOSITIONS WITH HIGH QUANTITIES OF UV STABILIZERS BASF SE (DE) 2017-12-20 EP disclosed
EP-3227016-A1 MICROCAPSULES BASF SE (DE) 2017-10-11 EP disclosed
EP-2994201-A1 AGENT CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-16 EP disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 US disclosed
WO-2014180818-A1 AGENT CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2014-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES SDHB, SDHA, MCM5 L3MBTL1 4851/4885ADORA2A 3849/4885ADORA1 3930/4885
US-20170360660-A1 MICROCAPSULES ADH5, IPMK, CHKB L3MBTL1 4278/4885ADORA2A 4101/4885ADORA1 4666/4885
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA L3MBTL1 4600/4885ADORA2A 2835/4885ADORA1 3113/4885
US-10709645-B2 Microcapsules ADH5, IPMK, CHKB L3MBTL1 4278/4885ADORA2A 4101/4885ADORA1 4666/4885
US-20230293405-A1 Compositions Comprising UV-Filters and One or More (Bio)-Alkanediols AHR, DHCR24, DDC L3MBTL1 4310/4885ADORA2A 3490/4885ADORA1 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.