SCHEMBL17130787

SCHEMBL17130787

C=CCC(C)(CCC=C(C)C)C(C)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.47
HIF1A Q16665 4/20 0.35
EPAS1 Q99814 4/20 0.35
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17106395 1.00 ALOX15 (0.47) ALOX15HIF1AEPAS1TSHRALDH1A1
SCHEMBL14323203 0.83 ALOX15 (0.34) ALOX15
SCHEMBL17131591 0.79 ALOX15 (0.42) ALOX15HIF1AEPAS1TSHRALDH1A1
SCHEMBL17106377 0.79 ALOX15 (0.42) ALOX15HIF1AEPAS1TSHRALDH1A1
SCHEMBL11215850 0.75 ALOX15 (0.61) ALOX15HIF1AEPAS1TSHR
SCHEMBL25252922 0.73 ALOX15 (0.59) ALOX15HIF1AEPAS1TSHR
SCHEMBL27487614 0.72
SCHEMBL14322479 0.72 ALOX15 (0.47) ALOX15HIF1AEPAS1TSHRALDH1A1
SCHEMBL14330208 0.72 ALOX15 (0.47) ALOX15HIF1AEPAS1TSHRALDH1A1
SCHEMBL12032019 0.72 MAPK1 (0.32) ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160289593-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-10-06 US disclosed
US-20160289593-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-10-06 US disclosed
WO-2015148743-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2015-10-01 WO disclosed
US-20150275132-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2015-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289593-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 ALOX15 599/4885HIF1A 1661/4885EPAS1 502/4885
US-20150275132-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 ALOX15 599/4885HIF1A 1661/4885EPAS1 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.