Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713056 | 0.97 | MAPK1 (0.67) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1712968 | 0.82 | MAPT (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1712641 | 0.80 | MAPT (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1713488 | 0.78 | ALDH1A1 (0.62) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1712558 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL1712735 | 0.74 | ALDH1A1 (0.57) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1713199 | 0.73 | MEN1 (0.57) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1713300 | 0.73 | ALDH1A1 (0.56) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5244127 | 0.72 | MEN1 (0.72) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5282637 | 0.72 | MEN1 (0.72) | MAPK1ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252587-B1 | PIPERIDINE SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-20 | — | — | EP | claimed |