SCHEMBL11546

SCHEMBL11546

Nc1ccccc1Sc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
NPSR1 Q6W5P4 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
POLB P06746 2/20 0.50
CYP1A2 P05177 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
PDE7A Q13946 1/20 0.47
DHFR P00374 1/20 0.46
GFER P55789 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613097 1.00 MAPT (0.56) MAPTMEN1KMT2ANPSR1APOBEC3G
Hydrochloric Acid SCHEMBL5211034 0.98 MAPT (0.54) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL17847477 0.89 MAPT (0.46) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL3095695 0.86 CYP3A4 (0.56) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL433052 0.84 DHFR (0.46) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL713707 0.84 MEN1 (0.68) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL29869345 0.84 MEN1 (0.68) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL2614720 0.82 DHFR (0.49) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL546833 0.82 DHFR (0.49) MAPTMEN1KMT2ANPSR1APOBEC3G
SCHEMBL1713296 0.82 CYP1A2 (0.53) MAPTMEN1KMT2ANPSR1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108623561-B Method for preparing panenonic acid compound 中国海洋大学 2025-04-01 CN claimed
CN-117925000-A Preparation method of high-temperature-resistant ink 浙江浦江永进工贸有限公司 2024-04-26 CN claimed
CN-117624450-A High-temperature-resistant PMMA foam material and preparation method thereof 浙江中科恒泰新材料科技有限公司 2024-03-01 CN claimed
CN-115746181-B IVB-group tridentate catalyst, synthesis method and application 郑州大学 2023-12-29 CN claimed
CN-115490797-B Preparation method for improving creep property of suspended PTFE 浙江巨圣氟化学有限公司 2023-11-14 CN claimed
CN-116262796-A Hyperbranched cycloolefin copolymer and preparation method thereof 中山大学 2023-06-16 CN claimed
CN-113072207-B Urban river ecological management system and method 中设设计集团中原建设工程有限公司 2023-05-26 CN claimed
CN-115785739-A Novel organic gold paste, preparation method and application 中国石油大学(华东) 2023-03-14 CN claimed
CN-115490797-A Preparation method for improving creep property of suspension PTFE (polytetrafluoroethylene) 浙江巨圣氟化学有限公司 2022-12-20 CN claimed
CN-113224319-B Preparation method of nitrogen-sulfur co-doped carbon-coated transition metal nano sulfide electrochemical oxygen catalyst 广西大学 2022-08-09 CN claimed
EP-1615698-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2006-01-18 EP claimed
EP-1615666-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2006-01-18 EP claimed
WO-2005028459-A1 PREPARATION METHOD FOR QUETIAPINE FERMION OY (FI) 2005-03-31 WO claimed
WO-2005012274-A1 PROCESS FOR THE PREPARATION OF 11-(1-PIPERAZINYL)DIBENZO `B, F! `1 ,4!-THIAZEPINE, AN INTERMEDIATE IN THE SYNTHESIS OF THE ANTIPSYCHOTIC DRUG QUETIAPINE HELM AG (DE) 2005-02-10 WO claimed
US-20050004367-A1 Sulfonamide derivatives DU DANIEL Y (US) 2005-01-06 US claimed
WO-2004089470-A2 NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089416-A2 COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
WO-2004089415-A2 COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST NOVO NORDISK A/S (DK) 2004-10-21 WO claimed
US-5260388-A Reacting aromatic diamine with tetracarboxylic anhydride in presence of aromatic dicarboxylic anhydride or monoamine, imidizing; low dielectric characteristics; electronics MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-09 US claimed
US-4212959-A MALEIMIDE COMPOUNDS, DIEPOXY COMPOUNDS; NON-SOLVENT VARNISH MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1980-07-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004367-A1 Sulfonamide derivatives AR, SULT2A1, SHBG MAPT 3401/4885MEN1 1772/4885KMT2A 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.