Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17133240 | 0.92 | CA3 (0.36) | EPHX1EPHX2PAOX | |
| SCHEMBL17133243 | 0.92 | EPHX1 (0.57) | EPHX1EPHX2ACHEATM | |
| SCHEMBL17133236 | 0.86 | EPHX1 (0.47) | EPHX1EPHX2ACHEPAOXATM | |
| SCHEMBL17133211 | 0.86 | EPHX1 (0.50) | EPHX1EPHX2ACHEPAOX | |
| SCHEMBL17133272 | 0.86 | CA3 (0.33) | EPHX1 | |
| SCHEMBL12972152 | 0.85 | EPHX1 (0.55) | EPHX1EPHX2ACHEPAOXATM | |
| SCHEMBL16412053 | 0.85 | EPHX1 (0.45) | EPHX1EPHX2ATM | |
| SCHEMBL272668 | 0.85 | TSHR (0.44) | EPHX1ACHEPAOX | |
| SCHEMBL17133219 | 0.84 | KEAP1 (0.35) | PAOX | |
| SCHEMBL6284969 | 0.83 | EPHX1 (0.68) | EPHX1EPHX2ACHEPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144384-A1 | SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP | EVONIK DEGUSSA GMBH (DE) | 2015-10-01 | — | — | WO | disclosed |