Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972152 | 0.93 | EPHX1 (0.55) | EPHX1EPHX2ACHEATM | |
| SCHEMBL16412053 | 0.92 | EPHX1 (0.45) | EPHX1EPHX2ATM | |
| SCHEMBL17133232 | 0.92 | EPHX1 (0.49) | EPHX1EPHX2ACHEATM | |
| SCHEMBL18372173 | 0.85 | EPHX1 (0.39) | EPHX1EPHX2 | |
| SCHEMBL14865799 | 0.85 | EPHX1 (0.39) | EPHX1EPHX2 | |
| SCHEMBL12794858 | 0.84 | EPHX1 (0.38) | EPHX1EPHX2 | |
| SCHEMBL17133238 | 0.84 | EPHX1 (0.55) | EPHX1EPHX2ACHEATM | |
| SCHEMBL17133244 | 0.83 | KEAP1 (0.42) | EPHX1EPHX2 | |
| SCHEMBL13907618 | 0.83 | EPHX1 (0.59) | EPHX1EPHX2ACHE | |
| SCHEMBL17133273 | 0.82 | EPHX1 (0.42) | EPHX1EPHX2ACHEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015144384-A1 | SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP | EVONIK DEGUSSA GMBH (DE) | 2015-10-01 | — | — | WO | disclosed |