Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17133243 | 0.93 | EPHX1 (0.57) | EPHX1EPHX2ATMACHE | |
| SCHEMBL16412053 | 0.92 | EPHX1 (0.45) | EPHX1EPHX2MEN1KMT2AATM | |
| SCHEMBL14865799 | 0.85 | EPHX1 (0.39) | EPHX1EPHX2 | |
| SCHEMBL18372173 | 0.85 | EPHX1 (0.39) | EPHX1EPHX2 | |
| SCHEMBL17133232 | 0.85 | EPHX1 (0.49) | EPHX1EPHX2ATMPAOXACHE | |
| SCHEMBL12794858 | 0.84 | EPHX1 (0.38) | EPHX1EPHX2PAOX | |
| SCHEMBL17133244 | 0.83 | KEAP1 (0.42) | EPHX1EPHX2MTNR1AKMT2A | |
| SCHEMBL10557593 | 0.83 | EPHX1 (0.57) | EPHX1KDM4CEPHX2SMN1; SMN2MTNR1A | |
| SCHEMBL7603361 | 0.82 | KMT2A (0.43) | EPHX1KMT2AACHE | |
| SCHEMBL17133240 | 0.81 | CA3 (0.36) | EPHX1EPHX2MEN1KMT2APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | KRT18, FABP4, APMAP | EPHX1 2287/4885KDM4C 1610/4885EPHX2 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.