Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.40 |
| ▸ | DRD3 | P35462 | 8/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | DRD5 | P21918 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607374 | 1.00 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL28142221 | 0.98 | DRD2 (0.39) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL27745146 | 0.94 | CXCR2 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL17048114 | 0.83 | EPAS1 (0.37) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL17284193 | 0.83 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL19971751 | 0.82 | PTPN1 (0.39) | ADORA2AADORA1 | |
| SCHEMBL1712875 | 0.81 | DRD2 (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30387806 | 0.81 | HSD11B1 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL14985330 | 0.81 | HSD11B1 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30706241 | 0.81 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240363902-A1 | Electrolyte Additives that Reduce Gas Evolution in Li ion Batteries | StoreDot Ltd. (IL) | 2024-10-31 | — | — | US | claimed |
| CN-118146238-A | Polycyclic spiro indoline compound and preparation method thereof | 广西科技大学 | 2024-06-07 | — | — | CN | claimed |
| CN-112979551-B | Synthesis method of pyrazolone containing quaternary carbon atoms | 安徽师范大学 | 2023-11-24 | — | — | CN | claimed |
| CN-116947685-A | Method for synthesizing N, N-diaryl-O-allylhydroxylamine compound from nitroarene | 安徽中烟工业有限责任公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116947686-A | N-aryl-N-alkyl-O-allylhydroxylamine compound and synthesis method thereof | 安徽中烟工业有限责任公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116675663-A | Preparation method of coumarin compound and application of coumarin compound in neuroprotection | 兰州交通大学 | 2023-09-01 | — | — | CN | claimed |
| CN-116621745-A | (2-phenoxyphenyl) phenyl thioether compound and synthesis method thereof | 华北水利水电大学 | 2023-08-22 | — | — | CN | claimed |
| CN-111662339-B | Ferrocenyl-containing arylamine compound and synthesis method thereof | 安徽师范大学 | 2023-03-07 | — | — | CN | claimed |
| US-20230050863-A1 | DICATIONIC FLUORESCENT DYES | ROCHE MOLECULAR SYSTEMS, INC. | 2023-02-16 | — | — | US | claimed |
| CN-113072500-B | Synthetic method of dibenzo [ b, e ] azepine compound | 淮北师范大学 | 2023-01-20 | — | — | CN | claimed |
| US-9206196-B1 | Derivatives of benzoxazino quinoline, benzoxazino isoquinoline and processes for their preparation | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (US) | 2015-12-08 | — | — | US | claimed |
| WO-2015128878-A1 | NOVEL BENZOXAPHOSPHOLE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-03 | — | — | WO | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| US-9056817-B2 | Arylated β-dicarbonyl compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-16 | — | — | US | claimed |
| WO-2014207761-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | claimed |
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-14 | — | — | US | claimed |
| EP-2755945-A1 | ARYLATED beta-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2014-07-23 | — | — | EP | claimed |
| WO-2013038427-A1 | ARYLATED β-DICARBOIMYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-21 | — | — | WO | claimed |
| US-20120177561-A1 | NANOSTRUCTURES AND METHODS FOR CHEMICALLY SYNTHESIZING NANOSTRUCTURES | TRUSTEES OF BOSTON COLLEGE (US) | 2012-07-12 | — | — | US | claimed |
| WO-2010151307-A1 | NANOSTRUCTURES AND METHODS FOR CHEMICALLY SYNTHESIZING NANOSTRUCTURES | TRUSTEES OF BOSTON COLLEGE (US) | 2010-12-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228592-A1 | ARYLATED BETA-DICARBONYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | CYP51A1, DDT, CYP3A4 | DRD2 633/4885DRD3 1398/4885DRD4 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.