Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.40 |
| ▸ | DRD3 | P35462 | 8/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | DRD5 | P21918 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713611 | 1.00 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL28142221 | 0.98 | DRD2 (0.39) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL27745146 | 0.94 | CXCR2 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL17048114 | 0.83 | EPAS1 (0.37) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL17284193 | 0.83 | DRD2 (0.40) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL19971751 | 0.82 | PTPN1 (0.39) | ADORA2AADORA1 | |
| SCHEMBL1712875 | 0.81 | DRD2 (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30387806 | 0.81 | HSD11B1 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL14985330 | 0.81 | HSD11B1 (0.38) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30706241 | 0.81 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146238-A | Polycyclic spiro indoline compound and preparation method thereof | 广西科技大学 | 2024-06-07 | — | — | CN | claimed |
| CN-112876503-B | Borate compound for cancer boron neutron capture therapeutic medicine and preparation thereof | 中国科学院兰州化学物理研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-122059864-A | Azido-containing seleno-ether compound, seleno-oxide, preparation methods and application | 福建师范大学 | 2026-05-19 | — | — | CN | disclosed |
| EP-4719605-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GlaxoSmithKline Intellectual Property (No.4) Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246862-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |
| CN-118146238-A | Polycyclic spiro indoline compound and preparation method thereof | 广西科技大学 | 2024-06-07 | — | — | CN | disclosed |
| EP-4267561-A1 | SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLX | Baylor College of Medicine (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-116783183-A | 1- (2- (4-cyclopropyl-1H-1, 2, 3-triazol-1-yl) acetyl) -4-hydroxy-N- (benzyl) pyrrolidine-2-carboxamide derivatives as VHL inhibitors for the treatment of anemia and cancer | 基因泰克公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116496289-A | Synthesis and application of membrane-targeted naphthalene endoperoxides | 大连理工大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022140643-A1 | SMALL-MOLECULE MODULATORS OF THE ORPHAN NUCLEAR RECEPTOR TLX | BAYLOR COLLEGE OF MEDICINE (US) | 2022-06-30 | — | — | WO | disclosed |
| CN-112876503-B | Borate compound for cancer boron neutron capture therapeutic medicine and preparation thereof | 中国科学院兰州化学物理研究所 | 2022-04-29 | — | — | CN | disclosed |