Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17136351 | 0.94 | HCRTR1 (0.57) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136552 | 0.94 | HCRTR1 (0.55) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136546 | 0.94 | TRPA1 (0.54) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136573 | 0.92 | HCRTR1 (0.56) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136454 | 0.91 | TRPA1 (0.55) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136503 | 0.90 | HTR2C (0.52) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136431 | 0.90 | MMP8 (0.51) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136378 | 0.89 | MMP8 (0.58) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17136509 | 0.88 | TRPA1 (0.59) | HCRTR1HCRTR2TRPA1MMP8MMP12 | |
| SCHEMBL17199917 | 0.87 | HCRTR1 (0.53) | HCRTR1HCRTR2TRPA1MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937335-A1 | HETEROCYCLIC AMIDE DERIVATIVE, AND MEDICINE CONTAINING SAME | Ajinomoto Co., Inc. (JP) | 2015-10-28 | — | — | EP | disclosed |
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | TRPA1, TRPV1, TRPV2 | HCRTR1 97/4885HCRTR2 45/4885TRPA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.