SCHEMBL171366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13490510	0.86	ENPP2 (0.49)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL13490610	0.81	BCL9 (0.52)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL171371	0.79	JAK2 (0.48)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL13490506	0.78	JAK2 (0.55)	JAK2JAK1TYK2JAK3PRMT5
	SCHEMBL169477	0.77	JAK2 (0.49)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL171529	0.77	JAK2 (0.50)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL13490730	0.77	JAK2 (0.50)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL13490667	0.77	JAK2 (0.48)	JAK2JAK1TYK2JAK3BCL9
	SCHEMBL171313	0.77	SMN1; SMN2 (0.57)	JAK2JAK1TYK2JAK3PRMT5
	SCHEMBL29087342	0.77	SMN1; SMN2 (0.59)	JAK2JAK1TYK2JAK3BCL9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.