SCHEMBL17138135

SCHEMBL17138135

CC(=O)CCC(=O)Oc1cccc(OC(=O)CCC(C)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
KMT2A Q03164 4/20 0.50
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.48
ACHE P22303 2/20 0.47
CYP3A4 P08684 1/20 0.47
EGFR P00533 1/20 0.43
ERBB2 P04626 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17138191 0.89 EGFR (0.50) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL17138133 0.89 LMNA (0.49) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL5711151 0.86 ALDH1A1 (0.57) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL3451753 0.85 LMNA (0.56) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL421378 0.82 BCL9 (0.53) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL18333384 0.82 KMT2A (0.57) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL26564896 0.80 LMNA (0.61) LMNAKMT2AALDH1A1MEN1ACHE
SCHEMBL17138157 0.79 KMT2A (0.54) LMNAKMT2AMAPTALDH1A1MEN1
SCHEMBL12742253 0.79 LMNA (0.58) LMNAKMT2AMAPTALDH1A1HTT
SCHEMBL14579683 0.79 CYP1A2 (0.62) LMNAKMT2AMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 LMNA 1443/4885KMT2A 580/4885MAPT 4348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.