SCHEMBL5711151

SCHEMBL5711151

CC(=O)CCC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.57
KMT2A Q03164 5/20 0.57
MAPT P10636 4/20 0.57
HTT P42858 2/20 0.57
LMNA P02545 1/20 0.57
HSD17B10 Q99714 1/20 0.57
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
ELANE P08246 2/20 0.47
CYP19A1 P11511 1/20 0.47
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSP90AA1 P07900 1/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43742 0.89 KMT2A (0.61) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL14276948 0.89 PRSS1 (0.54) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL30593894 0.87 KMT2A (0.59) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL17138135 0.86 LMNA (0.52) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL383482 0.86 KMT2A (0.57) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL5001696 0.84 ALDH1A1 (0.81) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL6554235 0.83 KMT2A (0.55) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL2058361 0.83 ALDH1A1 (0.55) ALDH1A1KMT2AMAPTHTTLMNA
Di(Hydroxyethyl)Ether SCHEMBL12971202 0.83 KMT2A (0.42) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL23843934 0.82 KMT2A (0.60) ALDH1A1KMT2AMAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113767097-B Prodrugs of caspase inhibitors 株式会社LG化学 2025-03-14 CN disclosed
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof AJINOMOTO CO., INC. (JP) 2024-07-02 US disclosed
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 US disclosed
CN-104774607-B The fluorescent probe of single-minded identification bivalent cupric ion and application in a kind of aqueous phase 济南大学 2016-08-24 CN disclosed
CN-104774607-A Fluorescent probe for specially identifying bivalent copper ions in water phase and application thereof UNIV JINAN 2015-07-15 CN disclosed
US-20070191263-A1 Valency platform molecules comprising aminooxy groups LA JOLLA PHARMACEUTICAL COMPANY (US) 2007-08-16 US disclosed
EP-1732876-A1 PREPARATION OF LEVULINIC ACID ESTERS FROM ALPHA-ANGELICA LACTONE AND ALCOHOLS E.I.Du pont de nemours and company (US) 2006-12-20 EP disclosed
WO-2005097724-A1 PREPARATION OF LEVULINIC ACID ESTERS FROM ALPHA-ANGELICA LACTONE AND ALCOHOLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-10-20 WO disclosed
US-20050210738-A1 Preparation of levulinic acid esters from alpha-angelica lactone and alcohols E. I. DU PONT DE NEMOURS AND COMPANY 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191263-A1 Valency platform molecules comprising aminooxy groups DAO, PAM, BCAT2 ALDH1A1 2138/4885KMT2A 457/4885MAPT 2550/4885
US-20050210738-A1 Preparation of levulinic acid esters from alpha-angelica lactone and alcohols ADH1C, ADH1A, ADH5 ALDH1A1 6/4885KMT2A 1284/4885MAPT 1918/4885
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 ALDH1A1 1047/4885KMT2A 310/4885MAPT 2513/4885
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof SPPL2B, CSTB, SPPL2A ALDH1A1 1832/4885KMT2A 2873/4885MAPT 4288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.