Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154613 | 0.90 | ADRB2 (0.56) | GPBAR1ADRB2ADRB1LMNA | |
| SCHEMBL1581657 | 0.87 | GPBAR1 (0.53) | GPBAR1FFAR1TSHRMAPK1ADRB2 | |
| SCHEMBL4970580 | 0.87 | MAOB (0.50) | GPBAR1FFAR1LMNAKDM4E | |
| SCHEMBL11162901 | 0.87 | GPBAR1 (0.50) | GPBAR1FFAR1TSHRMAPK1ADRB2 | |
| SCHEMBL19122314 | 0.87 | KDM4E (0.56) | GPBAR1FFAR1TSHRLMNAKDM4E | |
| SCHEMBL2500159 | 0.85 | FFAR1 (0.61) | GPBAR1FFAR1MTNR1AMTNR1BADRB2 | |
| SCHEMBL28294103 | 0.85 | FFAR1 (0.61) | GPBAR1FFAR1MTNR1AMTNR1BADRB2 | |
| SCHEMBL8109516 | 0.84 | GPBAR1 (0.48) | GPBAR1FFAR1TSHRMAPK1HIF1A | |
| SCHEMBL19291755 | 0.84 | GPBAR1 (0.48) | GPBAR1FFAR1HIF1AGRM2 | |
| SCHEMBL12094232 | 0.84 | GPBAR1 (0.48) | GPBAR1FFAR1TSHRTLR8MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | GPBAR1 3596/4885FFAR1 214/4885TSHR 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.