Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138170 | 0.84 | GPBAR1 (0.60) | GPBAR1FFAR1MCHR1ADRB2ADRB1 | |
| SCHEMBL10154613 | 0.80 | ADRB2 (0.56) | GPBAR1ADRB2ADRB1LMNA | |
| SCHEMBL1581657 | 0.77 | GPBAR1 (0.53) | GPBAR1FFAR1ADRB2ADRB1TSHR | |
| SCHEMBL11162901 | 0.77 | GPBAR1 (0.50) | GPBAR1FFAR1ADRB2ADRB1GRM2 | |
| SCHEMBL4970580 | 0.77 | MAOB (0.50) | GPBAR1FFAR1LMNA | |
| SCHEMBL19122314 | 0.77 | KDM4E (0.56) | GPBAR1FFAR1TSHRLMNAGPR88 | |
| SCHEMBL2500159 | 0.75 | FFAR1 (0.61) | GPBAR1FFAR1ADRB2ADRB1TLR8 | |
| SCHEMBL28294103 | 0.75 | FFAR1 (0.61) | GPBAR1FFAR1ADRB2ADRB1TLR8 | |
| SCHEMBL19291755 | 0.74 | GPBAR1 (0.48) | GPBAR1FFAR1GRM2HIF1A | |
| SCHEMBL12094232 | 0.74 | GPBAR1 (0.48) | GPBAR1FFAR1MCHR1TLR8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000169589-A | OPTICALLY ACTIVE ORGANOSILICON HOMOPOLYMER AND COPOLYMER | NIPPON TELEGR & TELEPH CORP <NTT> | 2000-06-20 | — | — | JP | disclosed |