SCHEMBL1714211

SCHEMBL1714211

COc1cc(OCC=C(C)CCC=C(C)C)c2ccc(=O)oc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 10/20 0.70
NDUFS8 O00217 2/20 0.67
COXFA4 O00483 2/20 0.67
NDUFAB1 O14561 2/20 0.67
NDUFA1 O15239 2/20 0.67
NDUFS4 O43181 2/20 0.67
NDUFB5 O43674 2/20 0.67
NDUFB3 O43676 2/20 0.67
NDUFC1 O43677 2/20 0.67
NDUFA2 O43678 2/20 0.67
NDUFS5 O43920 2/20 0.67
NDUFS7 O75251 2/20 0.67
NDUFS2 O75306 2/20 0.67
NDUFS6 O75380 2/20 0.67
NDUFB1 O75438 2/20 0.67
NDUFS3 O75489 2/20 0.67
NDUFB6 O95139 2/20 0.67
NDUFA3 O95167 2/20 0.67
NDUFB4 O95168 2/20 0.67
NDUFB8 O95169 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31135288 1.00 ALOX15 (0.70) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL1714204 1.00 ALOX15 (0.70) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL28772330 0.90 ALDH1A1 (0.64) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL25269817 0.83 NDUFS8 (0.68) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL28745065 0.81 MAOB (0.70) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL22922167 0.81 NDUFS8 (1.00) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL31237275 0.81 NDUFS8 (1.00) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL10703236 0.80 ALOX15 (1.00) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL10703243 0.80 ALOX15 (1.00) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1
SCHEMBL18292776 0.80 NDUFS8 (0.98) ALOX15NDUFS8COXFA4NDUFAB1NDUFA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098244-B2 Antibacterial agent TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-08-29 US claimed
WO-2006087039-A1 BROAD SPECTRUM ANTI VIRAL HERBAL COMPOSITION PROPHAREX SA (BE) 2006-08-24 WO claimed
JP-7025764-A None JP disclosed
EP-1786820-B1 9-(1',5'-DIMETHYL-1'-VINYL-4'-HEXENYL)-4-HYDROXY-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE AS ANTIBACTERIAL AGENT TAKASAGO PERFUMERY CO LTD (JP) 2011-07-20 EP disclosed
US-7122218-B2 Taste enhancer TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-10-17 US disclosed
US-7098244-B2 Antibacterial agent TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-08-29 US disclosed
WO-2006087039-A1 BROAD SPECTRUM ANTI VIRAL HERBAL COMPOSITION PROPHAREX SA (BE) 2006-08-24 WO disclosed
US-7060726-B2 Antibacterial agent TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-06-13 US disclosed
EP-1334665-B1 Taste enhancer and its use for taste enhancement TAKASAGO PERFUMERY CO LTD (JP) 2005-08-10 EP disclosed
US-20040180951-A1 Antibacterial agent HIRAMOTO TADAHIRO (JP) 2004-09-16 US disclosed
US-6752862-B2 COUMARIN ANALOG, A GLYCOSIDE OF THAT ANALOG, OR A PLANT EXTRACT CONTAINING THE COUMARIN ANALOG OR ITS GLYCOSIDE TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-06-22 US disclosed
US-20030157240-A1 Taste enhancer TAKASAGO INTERNATIONAL CORPORATION 2003-08-21 US disclosed
EP-1334665-A1 Taste enhancer; process for its production; food, drink, composition for the oral cavity comprising said taste enhancer; method of taste enhancement Takasago International Corporation (JP) 2003-08-13 EP disclosed
WO-2003059309-A1 COMPOSITION BASED ON 5,7 DMC AND/OR BERGAMOTTIN CHAPELLE ANDRE (BE) 2003-07-24 WO disclosed
US-20030068389-A1 Antibacterial agent TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-04-10 US disclosed
US-20030024440-A1 Color fading/discoloration preventive agent TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-02-06 US disclosed
EP-1240832-A2 Antibacterial agent Takasago International Corporation (JP) 2002-09-18 EP disclosed
EP-1240831-A2 Color fading/discoloration preventive agent Takasago International Corporation (JP) 2002-09-18 EP disclosed
JP-H0725764-A ANTIBACTERIAL AGENT POKKA CORP 1995-01-27 JP disclosed