Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.54 |
| ▸ | NDUFS8 | O00217 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28745065 | 0.90 | MAOB (0.70) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL31135288 | 0.90 | ALOX15 (0.70) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL1714211 | 0.90 | ALOX15 (0.70) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL1714204 | 0.90 | ALOX15 (0.70) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL25269817 | 0.81 | NDUFS8 (0.68) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| Citropten SCHEMBL29425178 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| Citropten SCHEMBL516577 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL28744737 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL18292782 | 0.77 | NDUFS8 (0.80) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 | |
| SCHEMBL29227420 | 0.76 | KDM4E (0.66) | ALDH1A1KDM4ECYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114558061-A | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2022-05-31 | — | — | CN | claimed |