Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19588952 | 0.92 | KCNK3 (0.46) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL17144855 | 0.90 | KCNK3 (0.43) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL15639828 | 0.79 | PTGS1 (0.55) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL17111294 | 0.78 | STIM1 (0.51) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL17064211 | 0.77 | LMNA (0.45) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL15639883 | 0.77 | PTGES (0.45) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL5332281 | 0.72 | KCNK3 (0.75) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL21022150 | 0.71 | LMNA (0.66) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL17064212 | 0.70 | SMN1; SMN2 (0.46) | KCNK3KCNK9PTGS1RXFP1F2R | |
| SCHEMBL26938134 | 0.70 | SMN1; SMN2 (0.46) | LMNAGAAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126335-B1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| EP-3126335-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
| WO-2015150300-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
| WO-2015150300-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | AADAC, CPS1, NAAA | KCNK3 3372/4885KCNK9 3539/4885PTGS1 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.