Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332281 | 0.88 | KCNK3 (0.75) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL2638776 | 0.87 | PTGS1 (0.70) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL8363754 | 0.86 | KCNK3 (0.64) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL3335567 | 0.86 | KCNK3 (0.59) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL678924 | 0.86 | PTGS1 (0.72) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL96040 | 0.86 | KCNK3 (0.59) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL20601679 | 0.84 | KCNK3 (0.66) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL21652266 | 0.83 | PTGES (0.62) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL30791183 | 0.83 | LMNA (0.69) | LMNAKCNK3KCNK9PTGS1PTPRC | |
| SCHEMBL6815792 | 0.83 | MEN1 (0.54) | LMNAKCNK3KCNK9PTGS1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384505-B | Therapeutic heterocyclic compounds | 吉利德科学公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-112384283-B | Therapeutic heterocyclic compounds | 吉利德科学公司 | 2023-08-15 | — | — | CN | disclosed |
| US-20200031801-A1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | GILEAD SCIENCES, INC. | 2020-01-30 | — | — | US | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031801-A1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | SDHA, SLC10A1, CYP11B2 | LMNA 1413/4885KCNK3 3280/4885KCNK9 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.