Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715022 | 0.84 | GFER (0.44) | HTR2CHTR2BHTR6HTR2ADRD2 | |
| SCHEMBL3796418 | 0.76 | SLC6A2 (0.49) | HTR2CHTR2BHTR6HTR2ADRD2 | |
| SCHEMBL9185398 | 0.72 | PKM (0.42) | HTR2CHTR6HTR2AKCNH2PKM | |
| SCHEMBL11968841 | 0.71 | KDM4E (0.42) | HTR2CHTR2AKCNH2DRD2ALDH1A1 | |
| SCHEMBL28440794 | 0.71 | SLC6A2 (0.41) | HTR2CHTR6 | |
| SCHEMBL28393842 | 0.70 | HTR2C (0.41) | HTR2CHTR2BHTR6HTR2A | |
| SCHEMBL6744243 | 0.70 | CA1 (0.44) | HTR6ALDH1A1USP2 | |
| SCHEMBL30407459 | 0.69 | CHRM2 (0.43) | HTR2CHTR6HTR2AKCNH2ALDH1A1 | |
| SCHEMBL28061774 | 0.69 | HTR6 (0.42) | HTR2CHTR6HTR2AKCNH2 | |
| SCHEMBL1885230 | 0.69 | NR1H4 (0.38) | HTR2CHTR6ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |