Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714647 | 0.72 | HTR2C (0.41) | PKMHTR6HTR2AHTR2CKCNH2 | |
| SCHEMBL30407459 | 0.71 | CHRM2 (0.43) | HTR6POLBHTR2AHTR2CKCNH2 | |
| SCHEMBL28061774 | 0.71 | HTR6 (0.42) | HTR6HTR2AHTR2CKCNH2CHRM2 | |
| SCHEMBL11968841 | 0.70 | KDM4E (0.42) | HTR2AHTR2CKCNH2ALDH1A1CHRM2 | |
| SCHEMBL7362762 | 0.70 | HTR6 (0.55) | HTR6ALDH1A1CHRM2CHRM1 | |
| SCHEMBL3796418 | 0.70 | SLC6A2 (0.49) | HTR6HTR2AHTR2CHTR1AHTR7 | |
| Fluoride SCHEMBL28061775 | 0.70 | HTR6 (0.41) | HTR6HTR2AHTR2CKCNH2CHRM2 | |
| SCHEMBL6744243 | 0.69 | CA1 (0.44) | HTR6MEN1KMT2AALDH1A1CHRM2 | |
| SCHEMBL7462033 | 0.68 | HTR6 (0.39) | HTR6HTR2AHTR2CKCNH2CHRM2 | |
| SCHEMBL9185391 | 0.68 | PKM (0.74) | PKMPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436734-B1 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| US-5250528-A | Cognition activators | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0436734-A1 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |