Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 12/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714647 | 0.84 | HTR2C (0.41) | HTR6HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL3796418 | 0.74 | SLC6A2 (0.49) | HTR6HTR2CHTR2BHTR2AHTR3E | |
| SCHEMBL30407459 | 0.70 | CHRM2 (0.43) | HTR6HTR2CHTR2AALDH1A1 | |
| SCHEMBL1715019 | 0.69 | GAA (0.76) | GFERMEN1KMT2AALDH1A1GAA | |
| SCHEMBL28440794 | 0.69 | SLC6A2 (0.41) | HTR6HTR2CADRB1CYP2C19MAPT | |
| SCHEMBL28393842 | 0.68 | HTR2C (0.41) | HTR6HTR2CHTR2BHTR2ADRD3 | |
| SCHEMBL2873088 | 0.68 | HTR3E (0.68) | HTR6HTR3EHTR3BADRB1DRD2 | |
| SCHEMBL9185398 | 0.68 | PKM (0.42) | MEN1KMT2AHTR6HTR2CHTR2A | |
| SCHEMBL19709331 | 0.67 | HTR2C (0.47) | HTR6HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL21359242 | 0.67 | HTR2C (0.47) | HTR6HTR2CHTR2BHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |