SCHEMBL17147185

SCHEMBL17147185

CC1=CC=C(c2ccc(C)s2)C1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 1/20 0.37
GFER P55789 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18853998 0.87 NPC1 (0.39) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL17147178 0.77 PTGS2 (0.43) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL14322034 0.77
SCHEMBL15274315 0.76
SCHEMBL29764 0.71 NPC1 (0.52) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL14621056 0.71 NPC1 (0.37) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL17135798 0.71 NPC1 (0.37) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL13187880 0.71 NPC1 (0.34) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12170048 0.69 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12982405 0.69 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023234136-A1 METHOD FOR PRODUCING FUNCTIONAL LAYER OF PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENT 東洋紡株式会社 2023-12-07 WO disclosed
US-9701771-B2 Substituted zirconocenes catalysts and methods of use in polymerization reactions BASELL POLYOLEFINE GMBH (DE) 2017-07-11 US disclosed
US-9701771-B2 Substituted zirconocenes catalysts and methods of use in polymerization reactions BASELL POLYOLEFINE GMBH (DE) 2017-07-11 US disclosed
US-9422380-B2 Non-bridged metallocene complexes for the polymerization of olefins Basell Polyolefine Wesseling (DE) 2016-08-23 US disclosed
US-9422380-B2 Non-bridged metallocene complexes for the polymerization of olefins Basell Polyolefine Wesseling (DE) 2016-08-23 US disclosed
US-9422319-B2 Bisaryl metallocenes and use thereof to produce polyolefins BASELL POLYOLEFINE GMBH (DE) 2016-08-23 US disclosed
US-9422319-B2 Bisaryl metallocenes and use thereof to produce polyolefins BASELL POLYOLEFINE GMBH (DE) 2016-08-23 US disclosed
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2015-10-08 US disclosed
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2015-10-08 US disclosed
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS BASELL POLYOLEFIN GMBH (DE) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284418-A1 BISARYL METALLOCENES AND USE THEREOF TO PRODUCE POLYOLEFINS PCBP1, PARG, PARN NPC1 4558/4885ALDH1A1 1970/4885HSD17B10 1188/4885
US-20150284490-A1 SUBSTITUTED ZIRCONOCENES CATALYSTS AND METHODS OF USE IN POLYMERIZATION REACTIONS MAOA, MPO, PARP1 NPC1 4650/4885ALDH1A1 1440/4885HSD17B10 744/4885
US-20150284489-A1 NON-BRIDGED METALLOCENE COMPLEXES FOR THE POLYMERIZATION OF OLEFINS PCBP1, MORF4L1, PPIL4 NPC1 2562/4885ALDH1A1 2151/4885HSD17B10 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.