SCHEMBL17147697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22064552	0.87	CYP3A4 (0.43)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6
	SCHEMBL11849441	0.82	TSHR (0.58)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6
	SCHEMBL11802291	0.79	CYP3A4 (0.53)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6
	SCHEMBL11849241	0.74	TSHR (0.72)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6
	Hydrochloric Acid SCHEMBL11852627	0.73	TSHR (0.64)	CYP3A4SMN1; SMN2HIF1ATSHRCLPP
	SCHEMBL2493279	0.70	TSHR (0.83)	CYP3A4SMN1; SMN2HIF1ATSHRGAA
	SCHEMBL17147698	0.70	CYP3A4 (0.66)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6
	SCHEMBL2494160	0.70	TSHR (0.67)	CYP3A4SMN1; SMN2TSHRCYP2D6GAA
	SCHEMBL18254991	0.69	CLPP (0.89)	CYP3A4SMN1; SMN2HIF1ACYP2D6DRD2
	SCHEMBL13559495	0.69	CYP3A4 (1.00)	CYP3A4SMN1; SMN2HIF1ATSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.