Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16978456 | 0.96 | NPY5R (0.35) | NPY5RGRIA4HCRTR2SLC6A2SLC6A4 | |
| SCHEMBL18284064 | 0.86 | GRIA4 (0.39) | NPY5RGRIA4HCRTR2 | |
| SCHEMBL3157843 | 0.86 | NPY5R (0.39) | NPY5RGRIA4HCRTR2 | |
| SCHEMBL16546460 | 0.83 | — | — | |
| SCHEMBL15172779 | 0.83 | ESR2 (0.42) | NPY5RGRIA4HCRTR2SLC6A2SLC6A4 | |
| SCHEMBL17147811 | 0.81 | NPC1 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18100603 | 0.80 | ESR2 (0.39) | NPY5RHCRTR2CYP19A1 | |
| SCHEMBL127018 | 0.79 | CYP11B2 (0.38) | NPY5RGRIA4HCRTR2 | |
| SCHEMBL8767030 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL14295821 | 0.77 | CYP11B2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481828-B2 | Liquid Crystal compound containing cyclobutyl group and difluoromethyleneoxy linking group, and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2016-11-01 | — | — | US | disclosed |
| US-9481828-B2 | Liquid Crystal compound containing cyclobutyl group and difluoromethyleneoxy linking group, and preparation method and use thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2016-11-01 | — | — | US | disclosed |
| US-20150284632-A1 | Liquid Crystal Compound Containing Cyclobutyl Group and Difluoromethyleneoxy Linking Group, and Preparation Method and Use Thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-10-08 | — | — | US | disclosed |
| US-20150284632-A1 | Liquid Crystal Compound Containing Cyclobutyl Group and Difluoromethyleneoxy Linking Group, and Preparation Method and Use Thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284632-A1 | Liquid Crystal Compound Containing Cyclobutyl Group and Difluoromethyleneoxy Linking Group, and Preparation Method and Use Thereof | CFB, CFL1, FASTKD1 | NPY5R 1307/4885GRIA4 1833/4885HCRTR2 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.