Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17149159 | 0.80 | LMNA (0.37) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL17149190 | 0.79 | MCL1 (0.42) | LMNAPTGS1TRPA1CACNA1CPTGS2 | |
| SCHEMBL17149163 | 0.77 | MEN1 (0.41) | LMNAPTGS1PTGS2 | |
| SCHEMBL17149148 | 0.77 | ALDH1A1 (0.38) | LMNAPTGS1TRPA1CACNA1CPTGS2 | |
| SCHEMBL17149151 | 0.75 | AAK1 (0.33) | — | |
| SCHEMBL14309168 | 0.74 | PTPN5 (0.42) | LMNAPTGS1PTPN5KIF11NPC1 | |
| SCHEMBL197335 | 0.72 | KIF11 (0.52) | LMNAPTPN5KIF11PTGS2NPC1 | |
| SCHEMBL12418424 | 0.71 | AHR (0.46) | LMNAPTGS1TRPA1CACNA1CPTPN5 | |
| SCHEMBL14707866 | 0.71 | RAPGEF4 (0.36) | LMNAALDH1A1GAAKDM4E | |
| SCHEMBL17149143 | 0.70 | LMNA (0.38) | LMNAPTGS1TRPA1CACNA1CPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815997-B2 | Organic electroluminescence device and ink composition | IDEMITSU KOSAN CO., LTD. (JP) | 2017-11-14 | — | — | US | disclosed |
| US-20150284580-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND INK COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2015-10-08 | — | — | US | disclosed |