Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508229 | 0.84 | CYP2A6 (0.46) | CYP2A6METAP2TGFBR1ALDH1A1NOS3 | |
| SCHEMBL24179779 | 0.80 | ALDH1A1 (0.41) | CYP2A6LMNAALDH1A1CCR1CCR8 | |
| SCHEMBL4159050 | 0.75 | CYP2A6 (0.43) | CYP2A6LMNAMETAP2TGFBR1ALDH1A1 | |
| SCHEMBL29000603 | 0.73 | CYP2A6 (0.39) | CYP2A6METAP2ALDH1A1NOS3NOS1 | |
| SCHEMBL17696988 | 0.73 | CYP2A6 (0.42) | CYP2A6METAP2ALDH1A1NOS3NOS1 | |
| SCHEMBL13825779 | 0.72 | CCR1 (0.48) | LMNAMETAP2ALDH1A1NOS3NOS1 | |
| SCHEMBL21181231 | 0.71 | LMNA (0.37) | CYP2A6LMNATGFBR1CCR1CCR8 | |
| SCHEMBL935465 | 0.69 | — | — | |
| SCHEMBL2039645 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL29324517 | 0.69 | KDM4E (0.42) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150285814-A1 | PHOSPHORESCENT DYE AND PHOSPHORESCENCE IMMUNOASSAY BY PEPTIDE DISPLACEMENT | UNIVERSITÄT LEIPZIG (DE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150285814-A1 | PHOSPHORESCENT DYE AND PHOSPHORESCENCE IMMUNOASSAY BY PEPTIDE DISPLACEMENT | NPPA, DNPEP, PTMS | CYP2A6 3515/4885LMNA 3592/4885METAP2 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.