Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563447 | 0.88 | NUDT1 (0.47) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL10394602 | 0.87 | CA12 (0.49) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL28734595 | 0.87 | NUDT1 (0.49) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL28734813 | 0.87 | NUDT1 (0.49) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL3605826 | 0.86 | TP53 (0.45) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL21056814 | 0.83 | KDM4C (0.50) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL29837473 | 0.83 | TSHR (0.60) | NUDT1TSHRCDC7DBF4CA12 | |
| SCHEMBL3515887 | 0.83 | TSHR (0.60) | NUDT1TSHRCDC7DBF4CA12 | |
| SCHEMBL5422256 | 0.82 | ALDH1A1 (0.43) | NUDT1TSHRCDC7DBF4TBXAS1 | |
| SCHEMBL18422040 | 0.82 | MKNK1 (0.60) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015152368-A1 | OXAZOLIDINONE AND OXAZINANONE DERIVATIVES | 大正製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |