Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17150217 | 0.82 | NUDT1 (0.51) | ALDH1A1NUDT1TP53CDC7DBF4 | |
| SCHEMBL10602219 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GLATBXAS1TSHRNPC1 | |
| SCHEMBL28734813 | 0.79 | NUDT1 (0.49) | ALDH1A1NUDT1TP53CDC7DBF4 | |
| SCHEMBL2563447 | 0.78 | NUDT1 (0.47) | ALDH1A1GLANUDT1TP53CDC7 | |
| SCHEMBL11592980 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GLATP53NPC1RAB9A | |
| SCHEMBL28734595 | 0.76 | NUDT1 (0.49) | ALDH1A1NUDT1TP53CDC7DBF4 | |
| SCHEMBL3605826 | 0.75 | TP53 (0.45) | ALDH1A1NUDT1TP53CDC7DBF4 | |
| SCHEMBL11592917 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GLAVDRTP53TSHR | |
| SCHEMBL277304 | 0.75 | TSHR (0.53) | ALDH1A1GLANUDT1TP53CDC7 | |
| SCHEMBL11592380 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GLAVDRTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123543-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123543-A1 | Novel compounds | C1R, CHRM2, CHRM1 | ALDH1A1 1964/4885GLA 3835/4885CHRNB2 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.