Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.41 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL3714624 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| Acrylamide SCHEMBL8498177 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL237862 | 0.87 | — | — | |
| SCHEMBL20547259 | 0.87 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL167151 | 0.87 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL12764449 | 0.87 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL422638 | 0.81 | — | — | |
| SCHEMBL572569 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRKMT2AHTTNPSR1 | |
| SCHEMBL20334621 | 0.80 | TET3 (0.41) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL25787464 | 0.80 | TET3 (0.41) | ALDH1A1TSHRFGFR4TET3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3100723-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3489232-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2019-05-29 | — | — | EP | disclosed |
| WO-2015154039-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-10-08 | — | — | WO | disclosed |