Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.58 |
| ▸ | TET3 | O43151 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | FBXL19 | Q6PCT2 | 5/20 | 0.42 |
| ▸ | CXXC5 | Q7LFL8 | 5/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.42 |
| ▸ | CXXC4 | Q9H2H0 | 5/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL8498177 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| Acrylamide SCHEMBL10658901 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL237862 | 0.89 | — | — | |
| SCHEMBL167151 | 0.89 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL20547259 | 0.89 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL12764449 | 0.89 | TET3 (0.47) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL17150702 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| Acrylamide SCHEMBL7045841 | 0.87 | MEN1 (0.45) | ALDH1A1TSHRFGFR4KMT2ABTK | |
| SCHEMBL20334621 | 0.82 | TET3 (0.41) | ALDH1A1TSHRFGFR4TET3KMT2A | |
| SCHEMBL25787464 | 0.82 | TET3 (0.41) | ALDH1A1TSHRFGFR4TET3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225388-A1 | COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING | Abbott Point Of Care, Inc. (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009082699-A1 | COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING | I-STAT CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
| EP-0356960-B1 | Stable polyacrylamide gels containing chaotropic agents | BIO RAD LABORATORIES (US) | 1994-01-05 | — | — | EP | disclosed |
| US-4950708-A | Stable polyacrylamide gels containing chaotropic agents | BIO-RAD LABORATORIES, INC. (US) | 1990-08-21 | — | — | US | disclosed |