Sugi Predict

Sugi Predict / Compounds / SCHEMBL17152008

SCHEMBL17152008

SCHEMBL17152008

CC1(C)c2ccccc2-c2c(-c3c(-c4nc(-c5ccc(-c6ccccc6)cc5)nc(-c5ccc(-c6ccccc6)cc5)n4)c4ccccc4c4ccccc34)cccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ ALDH1A1 P00352 4/20 0.33
▸ MAPT P10636 4/20 0.33
▸ HPGD P15428 4/20 0.33
▸ MEN1 O00255 4/20 0.33
▸ KMT2A Q03164 4/20 0.33
▸ ATM Q13315 3/20 0.33
▸ TSHR P16473 3/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ NFKB2 Q00653 1/20 0.33
▸ RELA Q04206 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ NPC1 O15118 1/20 0.32
▸ XBP1 P17861 1/20 0.32
▸ HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18386083 0.97 L3MBTL1 (0.37) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL21416092 0.94 L3MBTL1 (0.36) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL17152015 0.93 CYP1A2 (0.32) L3MBTL1MAPTHPGDMEN1KMT2A
SCHEMBL20405315 0.91 ENPP1 (0.36) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL18386089 0.90 ENPP1 (0.32) L3MBTL1ALDH1A1MAPTHPGDATM
SCHEMBL13487137 0.88 L3MBTL1 (0.32) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL17152006 0.87 L3MBTL1 (0.35) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL18386073 0.87 L3MBTL1 (0.37) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL17151617 0.86 L3MBTL1 (0.41) L3MBTL1ALDH1A1MAPTHPGDMEN1
SCHEMBL22059018 0.86 L3MBTL1 (0.41) L3MBTL1ALDH1A1MAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 — — US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 — — US disclosed
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2019-08-13 — — US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 — — US disclosed
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-01-19 — — US disclosed
WO-2015152651-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2015-10-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381572-B2 Heterocyclic compound and organic light-emitting element comprising same CRY1, CRY2, PER2 L3MBTL1 618/4885ALDH1A1 1107/4885MAPT 915/4885
US-20170018718-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 L3MBTL1 618/4885ALDH1A1 1107/4885MAPT 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.