Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152485 | 0.82 | TGM2 (0.49) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL17152538 | 0.80 | TGM2 (0.54) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17152412 | 0.75 | ALDH1A1 (0.46) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11054444 | 0.74 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1262239 | 0.73 | TGM2 (0.61) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12190068 | 0.72 | MAPT (0.60) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12172762 | 0.71 | NR4A1 (0.71) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18421181 | 0.70 | HRH3 (0.45) | MAPTKMT2ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL5567507 | 0.69 | P2RY1 (0.41) | MAPTNPC1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL17152313 | 0.69 | ALDH1A1 (0.46) | MEN1KMT2ATDP1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |