⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791424 | 0.77 | — | — | |
| SCHEMBL16670865 | 0.74 | F2 (0.47) | — | |
| SCHEMBL353636 | 0.73 | — | — | |
| SCHEMBL5466548 | 0.73 | MEN1 (0.42) | — | |
| SCHEMBL11065007 | 0.73 | — | — | |
| SCHEMBL5546776 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL15296475 | 0.72 | SLC6A2 (0.37) | — | |
| SCHEMBL8671567 | 0.72 | MMP8 (0.46) | — | |
| Hydrochloric Acid SCHEMBL719171 | 0.71 | — | — | |
| SCHEMBL190205 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | claimed |
| JP-1113388-A | — | — | None | — | — | JP | disclosed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| US-8034811-B2 | Hydroxamic acid esters and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2011-10-11 | — | — | US | disclosed |
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |
| CN-1906155-B | Novel hydroxamic acid ester derivant and pharmaceutical use thereof | LEO PHARMA AS | 2010-06-23 | — | — | CN | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| US-20070244117-A1 | Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof | LEO PHARMA A/S (DK) | 2007-10-18 | — | — | US | disclosed |
| EP-1070052-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051579-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 1999-10-14 | — | — | WO | disclosed |
| US-4828601-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1989-05-09 | — | — | US | disclosed |
| JP-H01113388-A | HERBICIDAL COMPOSITION | CHEVRON RES CO | 1989-05-02 | — | — | JP | disclosed |
| US-4824470-A | FOR GRASSES | CHEVRON RESEARCH COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0309271-A1 | Selective herbicides able additionally to control lateral buds in tobacco plants | CHEVRON RESEARCH COMPANY (US) | 1989-03-29 | — | — | EP | disclosed |
| US-4432786-A | Thienylmethoxyiminoalkyl cyclohexanedione herbicides | CHEVRON RESEARCH COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| US-4071533-A | Phosphoramidates and thiophosphoramidates as pesticides | ABBOTT LABORATORIES (US) | 1978-01-31 | — | — | US | disclosed |