Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.48 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137472 | 1.00 | PIN1 (0.52) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL17137470 | 1.00 | PIN1 (0.52) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL6830451 | 0.86 | PIN1 (0.49) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL25244025 | 0.85 | PIN1 (0.50) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL29414312 | 0.85 | PIN1 (0.50) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL7347037 | 0.85 | ALDH1A1 (0.56) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL25242832 | 0.85 | PIN1 (0.50) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL29414310 | 0.85 | PIN1 (0.50) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL7347042 | 0.85 | ALDH1A1 (0.56) | PIN1FAAHSMYD3PADI4PADI2 | |
| SCHEMBL25289343 | 0.82 | P2RX1 (0.52) | PIN1FAAHSMYD3PADI4PADI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284335-A1 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-10-08 | — | — | US | disclosed |
| US-20150284335-A1 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284335-A1 | Benzoimidazoles as prolyl hydroxylase inhibitors | EGLN3, EGLN2, P4HA1 | PIN1 83/4885FAAH 396/4885SMYD3 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.