SCHEMBL17154136

SCHEMBL17154136

CO[C@H]1OC(CO)[C@@H](O)C(C)[C@@H]1N=[N+]=[N-]

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 5/20 0.39
▸ ALDH1A1 P00352 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ FGF1 P05230 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CD209 Q9NNX6 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ OGA O60502 1/20 0.32
▸ MGAM O43451 2/20 0.32
▸ SI P14410 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14802349 1.00 LGALS8 (0.39) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL15293443 1.00 LGALS8 (0.39) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL15267646 0.88 LGALS8 (0.39) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL14864284 0.88 G6PD (0.33) —
SCHEMBL15267318 0.88 LGALS8 (0.39) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL15293425 0.88 G6PD (0.33) —
SCHEMBL14802348 0.88 G6PD (0.33) —
SCHEMBL23723836 0.88 LGALS8 (0.43) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL16504207 0.88 LGALS8 (0.43) LGALS8ALDH1A1HIF1AFGF1L3MBTL1
SCHEMBL14864297 0.88 LGALS8 (0.43) LGALS8ALDH1A1HIF1AFGF1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150284419-A1 METHOD FOR PREPARING FULLY PROTECTION HEPARIN PENTASACCHARIDE AND INTERMEDIATE THEREOF ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2015-10-08 — — US disclosed
US-8288527-B2 Oligo-aminosaccharide compound THE UNIVERSITY OF TOKYO (JP) 2012-10-16 — — US disclosed
US-20110003980-A1 Oligo-Aminosaccharide compound THE UNIVERSITY OF TOKYO (JP) 2011-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003980-A1 Oligo-Aminosaccharide compound DDOST, STT3A, STT3B LGALS8 625/4885ALDH1A1 4209/4885HIF1A 2701/4885
US-20150284419-A1 METHOD FOR PREPARING FULLY PROTECTION HEPARIN PENTASACCHARIDE AND INTERMEDIATE THEREOF HABP2, HPSE, PLG LGALS8 2747/4885ALDH1A1 2108/4885HIF1A 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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