Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FGF1 | P05230 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154136 | 1.00 | LGALS8 (0.39) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL15293443 | 1.00 | LGALS8 (0.39) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL15267646 | 0.88 | LGALS8 (0.39) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL14864284 | 0.88 | G6PD (0.33) | — | |
| SCHEMBL15267318 | 0.88 | LGALS8 (0.39) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL15293425 | 0.88 | G6PD (0.33) | — | |
| SCHEMBL14802348 | 0.88 | G6PD (0.33) | — | |
| SCHEMBL23723836 | 0.88 | LGALS8 (0.43) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL16504207 | 0.88 | LGALS8 (0.43) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 | |
| SCHEMBL14864297 | 0.88 | LGALS8 (0.43) | LGALS8ALDH1A1HIF1AFGF1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243018-B2 | Synthetic heparin pentasaccharides | DR. REDDY'S LABORATORIES, SA (CH) | 2016-01-26 | — | — | US | disclosed |
| US-20150284419-A1 | METHOD FOR PREPARING FULLY PROTECTION HEPARIN PENTASACCHARIDE AND INTERMEDIATE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-10-08 | — | — | US | disclosed |
| US-8987430-B2 | Efficient and scalable process for the manufacture of fondaparinux sodium | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-20150005485-A1 | SYNTHETIC HEPARIN PENTASACCHARIDES | ALCHEMIA LIMITED (AU) | 2015-01-01 | — | — | US | disclosed |
| US-20130261291-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130102764-A1 | PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-8420790-B2 | Efficient and scalable process for the manufacture of Fondaparinux sodium | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2013-04-16 | — | — | US | disclosed |
| US-8404833-B2 | Synthetic heparin disaccharides | ALCHEMIA LIMITED (AU) | 2013-03-26 | — | — | US | disclosed |
| US-8288515-B2 | Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120220759-A1 | SYNTHETIC HEPARIN DISACCHARIDES | ALCHEMIA LIMITED (AU) | 2012-08-30 | — | — | US | disclosed |
| US-20120208993-A1 | SYNTHETIC HEPARIN TRISACCHARIDES | ALCHEMIA LIMITED (AU) | 2012-08-16 | — | — | US | disclosed |
| US-20120116066-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110105418-A1 | PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284419-A1 | METHOD FOR PREPARING FULLY PROTECTION HEPARIN PENTASACCHARIDE AND INTERMEDIATE THEREOF | HABP2, HPSE, PLG | LGALS8 2747/4885ALDH1A1 2108/4885HIF1A 3276/4885 |
| US-20110105418-A1 | PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF | F11, TFPI, STS | LGALS8 2654/4885ALDH1A1 3144/4885HIF1A 2838/4885 |
| US-20120220759-A1 | SYNTHETIC HEPARIN DISACCHARIDES | HPSE, DDOST, STT3A | LGALS8 609/4885ALDH1A1 4468/4885HIF1A 1871/4885 |
| US-20150005485-A1 | SYNTHETIC HEPARIN PENTASACCHARIDES | HPSE, DDOST, STT3A | LGALS8 719/4885ALDH1A1 4652/4885HIF1A 2228/4885 |
| US-20120208993-A1 | SYNTHETIC HEPARIN TRISACCHARIDES | HPSE, SERPINC1, DDOST | LGALS8 910/4885ALDH1A1 4804/4885HIF1A 1981/4885 |
| US-20130102764-A1 | PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF | TFPI, PLG, PCSK6 | LGALS8 2126/4885ALDH1A1 2876/4885HIF1A 2731/4885 |
| US-20120116066-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | F11, F10, F2 | LGALS8 3253/4885ALDH1A1 2360/4885HIF1A 1878/4885 |
| US-20130261291-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | F11, F10, F2 | LGALS8 3253/4885ALDH1A1 2360/4885HIF1A 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.