Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.42 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511637 | 0.69 | PIN1 (0.50) | ALDH1A1TSHRPIN1FKBP1AFAAH | |
| SCHEMBL5308272 | 0.67 | TSHR (0.51) | ALDH1A1TSHRFKBP1APLAURPARP1 | |
| SCHEMBL5597594 | 0.66 | CYP2C9 (0.51) | ALDH1A1TSHRFKBP1AFAAHSMN1; SMN2 | |
| SCHEMBL8327592 | 0.65 | FKBP1A (1.00) | ALDH1A1TSHRFKBP1AL3MBTL1POLB | |
| SCHEMBL28218804 | 0.65 | MEN1 (0.74) | ALDH1A1TSHRFKBP1APOLBSMN1; SMN2 | |
| SCHEMBL1516144 | 0.65 | MAPT (0.82) | ALDH1A1TSHRFKBP1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL22479977 | 0.65 | PIN1 (1.00) | ALDH1A1TSHRPIN1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL68316 | 0.64 | MAPT (0.79) | ALDH1A1TSHRFKBP1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7068444 | 0.63 | FKBP1A (0.82) | ALDH1A1TSHRFKBP1AHTTPOLB | |
| SCHEMBL20181949 | 0.63 | FLT3 (0.69) | ALDH1A1TSHRHTTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583970-B1 | Certain chemical entities, compositions and methods comprising imidazopyrimidines | CYTOKINETICS INC (US) | 2015-10-14 | — | — | EP | disclosed |