Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.59 |
| ▸ | UNG | P13051 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | DDT | P30046 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561660 | 0.88 | TRIM24 (0.63) | AKR1C3AKR1C2UNGTRIM24TRIM33 | |
| SCHEMBL24197025 | 0.88 | DHFR (0.47) | AKR1C3AKR1C2UNGTRIM24TRIM33 | |
| SCHEMBL1347851 | 0.87 | ERN1 (0.49) | AKR1C3AKR1C2UNGTRIM24TRIM33 | |
| SCHEMBL6252539 | 0.84 | AKR1C3 (0.68) | AKR1C3AKR1C2NR1H4DDTKMO | |
| SCHEMBL17158362 | 0.83 | ALDH1A1 (0.56) | UNGTRIM24TRIM33ERN1ALDH1A1 | |
| SCHEMBL11837965 | 0.81 | ESR2 (0.53) | TRIM24TRIM33TTRALDH1A1KDM4E | |
| SCHEMBL28372111 | 0.81 | AKR1C3 (0.63) | AKR1C3AKR1C2NR1H4DDTKMO | |
| SCHEMBL26680871 | 0.80 | ESR2 (0.50) | AKR1C3AKR1C2ALDH1A1KDM4E | |
| SCHEMBL2562028 | 0.80 | ALDH1A1 (0.56) | AKR1C3AKR1C2UNGTRIM24TRIM33 | |
| SCHEMBL13038468 | 0.80 | ALDH1A3 (0.42) | AKR1C3AKR1C2ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522873-B2 | Biphenyl derivative, pharmaceutically acceptable salt thereof, and methods for preventing or treating inflammatory diseases or autoimmune diseases | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2016-12-20 | — | — | US | disclosed |
| US-20150291509-A1 | NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291509-A1 | NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT | CD47, MSR1, CD14 | AKR1C3 1159/4885AKR1C2 1362/4885UNG 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.