SCHEMBL17159758

SCHEMBL17159758

O=C(O)C1=CC=C(C(=O)O)C(=O)C1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
TTR P02766 2/20 0.34
PTPRC P08575 2/20 0.33
ALOX15 P16050 2/20 0.32
NFKB1 P19838 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
DAO P14920 2/20 0.32
NAPRT Q6XQN6 1/20 0.32
CYP1A2 P05177 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27723749 0.82 TSHR (0.41) TSHRTP53ALOX15ALDH1A1DAO
SCHEMBL14829070 0.72
SCHEMBL8565178 0.67 MAOA (0.35) TSHRTP53ALOX15NFKB1BLM
SCHEMBL19750859 0.67 TSHR (0.35) TSHRTP53ALOX15ALDH1A1DAO
SCHEMBL10964095 0.67 ALOX15 (0.36) TSHRTP53ALOX15NFKB1BLM
SCHEMBL10955588 0.65
SCHEMBL819903 0.63 CCR2 (0.35) TSHRTP53ALOX15BLMSMN1; SMN2
SCHEMBL22362544 0.60 TSHR (0.35) TSHRTP53ALOX15NFKB1BLM
SCHEMBL813575 0.60 TSHR (0.35) TSHRTP53ALOX15ALDH1A1DAO
SCHEMBL813574 0.60 TSHR (0.35) TSHRTP53ALOX15ALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4469182-A1 SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 Battelle Memorial Institute (US) 2024-12-04 EP disclosed
US-20230264138-A1 SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 BATTELLE MEMORIAL INSTITUTE 2023-08-24 US disclosed
WO-2023146800-A1 SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 BATTELLE MEMORIAL INSTITUTE (US) 2023-08-03 WO disclosed
US-20230233989-A1 SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 BATTELLE MEMORIAL INSTITUTE (US) 2023-07-27 US disclosed
US-10266737-B2 Adsorption systems using metal-organic frameworks ARKEMA INC. (US) 2019-04-23 US disclosed
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS PFAS, CHIA, PARN TSHR 4470/4885TP53 1667/4885TTR 2175/4885
US-10266737-B2 Adsorption systems using metal-organic frameworks PFAS, CHIA, PARN TSHR 4470/4885TP53 1667/4885TTR 2175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.