Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17159807 | 0.71 | HSD11B1 (0.59) | HSD11B1SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL6073754 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1GAALMNAKMT2A | |
| SCHEMBL18839845 | 0.70 | HCAR3 (0.40) | SMN1; SMN2ALDH1A1GAALMNAKMT2A | |
| SCHEMBL1647137 | 0.68 | KCNN4 (0.42) | HSD11B1SMN1; SMN2ALDH1A1KMT2ACYP2C9 | |
| SCHEMBL2288221 | 0.67 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10057825 | 0.67 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1LMNAADORA1KMT2A | |
| SCHEMBL25921188 | 0.67 | SDCBP (0.44) | SMN1; SMN2ALDH1A1AKR1C3AKR1C2NPC1 | |
| SCHEMBL25921249 | 0.67 | SDCBP (0.44) | SMN1; SMN2ALDH1A1AKR1C3AKR1C2NPC1 | |
| SCHEMBL1236135 | 0.66 | TP53 (0.35) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL828870 | 0.66 | HCAR3 (0.39) | SMN1; SMN2ALDH1A1GAAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206165-B2 | Tetrazolo hydrazine derivatives and pharmaceutical composition comprising same as active ingredient for preventing or treating cancer | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YEUNGNAM UNIVERSITY (KR) | 2015-12-08 | — | — | US | disclosed |
| US-20150291566-A1 | NOVEL TETRAZOLO HYDRAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YEUNGNAM UNIVERSITY (KR) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291566-A1 | NOVEL TETRAZOLO HYDRAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | API5, BAX, TP53 | HSD11B1 2437/4885SMN1; SMN2 4624/4885ALDH1A1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.